Reducing the Learning Domain by Using Image Processing to Diagnose COVID-19 from X-Ray Image

Over the last months, dozens of artificial intelligence (AI) solutions for COVID-19 diagnosis based on chest X-ray image analysis have been proposed. All of them with very impressive sensitivity and specificity results. However, its generalization and translation to the clinical practice are rather challenging due to the discrepancies between domain distributions when training and test data come from different sources. Consequently, applying a trained model on a new data set may have a problem with domain adaptation leading to performance degradation. This research aims to study the impact of image pre-processing on pre-trained deep learning models to reduce the learning domain. The dataset used in this research consists of 5,000 X-ray images obtained from different sources under two categories: negative and positive COVID-19 detection. We implemented transfer learning in 3 popular convolutional neural networks (CNNs), including VGG16, VGG19, and DenseNet169. We repeated the study following the same structure for original and pre-processed images. The pre-processing method is based on the Contrast Limited Adaptive Histogram Equalization (CLAHE) filter application and image registration. After evaluating the models, the CNNs that have been trained with pre-processed images obtained an accuracy score up to 1.2% better than the unprocessed ones. Furthermore, we can observe that in the 3 CNN models, the repeated misclassified images represent 40.9% (207/506) of the original image dataset with the erroneous result. In pre-processed ones, this percentage is 48.9% (249/509). In conclusion, image processing techniques can help to reduce the learning domain for deep learning applications

Towards simulated morality systems: Role-playing games as artificial societies

Computer role-playing games (RPGs) often include a simulated morality system as a core design element. Games' morality systems can include both god's eye view aspects, in which certain actions are inherently judged by the simulated world to be good or evil, as well as social simulations, in which non-player characters (NPCs) react to judgments of the player's and each others' activities. Games with a larger amount of social simulation have clear affinities to multi-agent systems (MAS) research on artificial societies. They differ in a number of key respects, however, due to a mixture of pragmatic game-design considerations and their typically strong embeddedness in narrative arcs, resulting in many important aspects of moral systems being represented using explicitly scripted scenarios rather than through agent-based simulations. In this position paper, we argue that these similarities and differences make RPGs a promising challenge domain for MAS research, highlighting features such as moral dilemmas situated in more organic settings than seen in game-theoretic models of social dilemmas, and heterogeneous representations of morality that use both moral calculus systems and social simulation. We illustrate some possible approaches using a case study of the morality systems in the game The Elder Scrolls IV: Oblivion

Active Re-identification Attacks on Periodically Released Dynamic Social Graphs

Active re-identification attacks pose a serious threat to privacy-preserving social graph publication. Active attackers create fake accounts to build structural patterns in social graphs which can be used to re-identify legitimate users on published anonymised graphs, even without additional background knowledge. So far, this type of attacks has only been studied in the scenario where the inherently dynamic social graph is published once. In this paper, we present the first active re-identification attack in the more realistic scenario where a dynamic social graph is periodically published. The new attack leverages tempo-structural patterns for strengthening the adversary. Through a comprehensive set of experiments on real-life and synthetic dynamic social graphs, we show that our new attack substantially outperforms the most effective static active attack in the literature by increasing the success probability of re-identification by more than two times and efficiency by almost 10 times. Moreover, unlike the static attack, our new attack is able to remain at the same level of effectiveness and efficiency as the publication process advances. We conduct a study on the factors that may thwart our new attack, which can help design graph anonymising methods with a better balance between privacy and utility

Extreme genomic erosion after recurrent demographic bottlenecks in the highly endangered Iberian lynx

Background: Genomic studies of endangered species provide insights into their evolution and demographic history, reveal patterns of genomic erosion that might limit their viability, and offer tools for their effective conservation. The Iberian lynx (Lynx pardinus) is the most endangered felid and a unique example of a species on the brink of extinction. Results: We generate the first annotated draft of the Iberian lynx genome and carry out genome-based analyses of lynx demography, evolution, and population genetics. We identify a series of severe population bottlenecks in the history of the Iberian lynx that predate its known demographic decline during the 20th century and have greatly impacted its genome evolution. We observe drastically reduced rates of weak-to-strong substitutions associated with GC-biased gene conversion and increased rates of fixation of transposable elements. We also find multiple signatures of genetic erosion in the two remnant Iberian lynx populations, including a high frequency of potentially deleterious variants and substitutions, as well as the lowest genome-wide genetic diversity reported so far in any species. Conclusions: The genomic features observed in the Iberian lynx genome may hamper short- and long-term viability through reduced fitness and adaptive potential. The knowledge and resources developed in this study will boost the research on felid evolution and conservation genomics and will benefit the ongoing conservation and management of this emblematic species

Graph Perturbation as Noise Graph Addition: A New Perspective for Graph Anonymization

Different types of data privacy techniques have been applied to graphs and social networks. They have been used under different assumptions on intruders’ knowledge. i.e., different assumptions on what can lead to disclosure. The analysis of different methods is also led by how data protection techniques influence the analysis of the data. i.e., information loss or data utility. One of the techniques proposed for graph is graph perturbation. Several algorithms have been proposed for this purpose. They proceed adding or removing edges, although some also consider adding and removing nodes. In this paper we propose the study of these graph perturbation techniques from a different perspective. Following the model of standard database perturbation as noise addition, we propose to study graph perturbation as noise graph addition. We think that changing the perspective of graph sanitization in this direction will permit to study the properties of perturbed graphs in a more systematic way